Last Updated on by Eat Better Move More

Do you feel the need to take magnesium L-threonate supplements? But you wonder what time of day should I take magnesium L-threonate? We were previously aware of how important Magnesium L-Threonate is for the maintenance of our bodily well-being.

It is useful as a supplement for treating depression, stress, and anxiety, in addition to being a protector of our brain cells. However, because magnesium supplements do not penetrate the blood-brain barrier very efficiently, the benefits of taking them are limited. The great news is that magnesium L-threonate might be able to fix that problem and provide us with entirely new benefits at the same time.

Magnesium L-Threonate: A Brief Explanation

The most recent addition to the family of magnesium chelates is magnesium L-threonate. Magnesium supplements are frequently chelated, which means that the magnesium molecules are bound to another molecule. This is done so that the magnesium can be absorbed more effectively. The magnesium supplement will be more stable and bioavailable as a result of this. It’s a fortunate turn of events.

A group of researchers at MIT came up with this most recent chelate, and they have since filed a patent for it. Magnesium L-threonate is capable of entering the brain and is simple to absorb. Once there, it has the potential to slow or even stop the ageing process in our brains. It has already been demonstrated to be beneficial for people suffering from anxiety disorders, cognitive impairment, and sleep difficulties. The fact that people who were given the supplements experienced slow brain ageing. It is the reason why this is such an intriguing new study.

How Does Magnesium L-Threonate Work?

What Time Of Day Should I Take Magnesium L-Threonate?

The majority of individuals do not obtain enough magnesium to meet their body’s requirements, and the majority of the medications that we take just make the problem worse. However, magnesium is essential for the proper operation of the brain.

The blood rather than the brain stores the majority of the magnesium that you consume daily. Therefore, the benefits it provides to us are restricted.

Magnesium L-threonate is fantastically useful in these three ways:

  • It passes across the barrier between the blood and the brain with ease.
  • This may increase the amount of protein which may promote the growth of new brain cells.
  • It promotes neuroplasticity in the body. This refers to the capacity of our brains to develop and adapt over time. 

Protector of the Mind

Because of a gradual loss of brain cells and synapses as we become older, our brains gradually become smaller. It should come as no surprise that this has significant negative effects on brain function. The Synapse is the little gap that exists between neurons and is responsible for the transmission of electric impulses from one neuron to the next.

The cells in our brains communicate with one another in this way so that we can process information. One neuron can have thousands of synapses. A drop in the number of synapses in the brain is a strong sign of cognitive decline.

Researchers have discovered that the best way to stop cognitive decline is to stop the loss of synapses and increase their density. This is the key to stopping cognitive decline. Magnesium L-threonate raises the amount of magnesium that is readily available in the brain, which in turn leads to an increase in neuronal density. 

The Investigations

Studies have been conducted on people in their 50s and 70s who were already experiencing symptoms of cognitive impairment, such as memory loss, anxiety, and trouble sleeping. During the study, each participant received either a placebo or a dose of magnesium L-threonate ranging from 1,500 mg to 2,000 mg per day. The study lasted for a total of 12 weeks.

Cognitive tests were administered by the researchers at 6-week intervals. Participants were given memory tasks that used their working memory, attention, executive function, and episodic memory (memory of an experience). 

The following was discovered by the researchers about the subjects:

It was found that there was a big increase in magnesium in the body. This was shown by the fact that there was a lot of magnesium in the urine and the number of red blood cells went up.

It is an indication of cognitive decline when we experience weaker brain function on some days than we do on other days. The subjects, on the other hand, had relatively modest deterioration in their cognitive function.

Researchers observed that there was a considerable improvement in participants’ brain function—much more so than there was any fluctuation. Their mental thinking speed and executive function execution both improved significantly. Some people reported seeing significant changes as early as the sixth week of treatment. By the end of week 12, all of the individuals had significantly advanced their cognitive growth in the areas that were tested. The most interesting thing was that the average brain age of the people got younger as the experiment went on. 

Brain Age

How old is a person’s brain? The cognitive function of an individual is what determines their “brain age,” not their chronological age. When determining a person’s brain age, both physiological metrics and mental performance are taken into consideration. In the investigations that were discussed earlier, the subjects had an average chronic age of 57.8 years, while their average brain age was 68.3 years. This was due to the decline in cognitive abilities that the individual had self-reported.

After the supplement was administered, there was a significant reduction in the average brain age of those who took part in the study, which went from 69.6 years to 60.9 years by the time the six weeks were done. After 12 weeks of participation in the trial, the participants’ brain ages had been further lowered by a cumulative 9.4 years. This represents a change in brain age of about ten years! 

Age Regenerator

Magnesium always has the effect of making the brain look younger. It has been known for a very long time that increasing the amount of magnesium in the brain will increase both synaptic density and neuroplasticity. The density of synapses: When there are more synapses, it is easier for the brain to process information.

Neuroplasticity refers to the brain’s capacity to change its structure, create new connections, and adapt to new environments. Neuroplasticity refers to the capacity of our brains to learn new things, change, and adjust to new circumstances.

Because magnesium is so beneficial to the brain, you may believe that taking a high-quality supplement is all that is required to get the necessary amount. However, one study found that even if your blood magnesium levels were increased by 300 percent, the levels in your brain would only increase by 19 percent. The blood-brain barrier is to blame for this phenomenon. It’s hard to say enough about how important it is to take a magnesium supplement that can quickly get through this barrier. 

Choosing a Beneficial Dietary Supplement

Magnesium L-threonate, often known as MgT, has been shown to reduce anxiety in animals by lowering the number of memories that are based on a generalized sense of fear. A consequence that may also occur in human beings. Check the label to see if it mentions magnesium L-threonate. Magnesium on its own is not sufficient.

When Should I Take the Magnesium L-threonate that I Bought?

What Time Of Day Should I Take Magnesium L-Threonate?

The majority of magnesium L-threonate supplements have similar dosing instructions and recommendations. If you are taking the supplement in capsule form, you should take one capsule upon waking up and another two capsules just before retiring to bed. If you choose to consume the supplement in powder form, then you should combine one level scoop of the powder with equal parts water and fruit juice and consume the mixture either in the morning or the evening.

It is recommended that a daily dose of 1,500 mg to 2,000 mg be taken. Although the labels of many products state 1,500 milligrams, the typical dosage is divided across three capsules. A dose of MgT that is 2,000 milligrams will have 144 milligrams of magnesium in it.

You can get MgT in a variety of generic forms, but if you like, you can also look for it under the brand name Magtein. Before taking MgT, you should discuss any medications you are currently taking with your primary care provider. It has a significant impact on the way several well-known medications work.

Drowsiness, headaches, and a feeling that more blood is flowing to the head are the only negative reactions that have been attributed to taking this dietary supplement. Additionally, there is a possibility of a slight laxative effect. It’s possible that the huge benefits of protecting your brain and living a happier life are more than enough to make up for the fact that these side effects might happen.


The magnesium L-threonate chelate is the most recent member to be added to the family of magnesium chelates. It has been demonstrated to be effective when used as a supplement for the treatment of anxiety, stress, and depression. Once it reaches our brains, it has the potential to significantly slow down or perhaps halt the natural ageing process that occurs there.

Magnesium L-threonate causes an increase in the quantity of magnesium that is readily available in the brain, which in turn leads to an increase in neuronal density. A significant indicator of cognitive decline is a decrease in the number of synapses, which are the connections that form between brain cells.

Stopping the destruction of these synapses is the most effective method for halting the progression of cognitive decline. People who took part in an experiment investigating the effects of magnesium supplementation on cognitive function and brain age reported considerable benefits in both areas.

After undergoing the treatment for a period of six weeks, the individuals’ average brain ages dropped from 68.3 years to 60.9 years.

This results in an almost ten-year difference in the brain’s age! Magnesium L-threonate, often known as MGT, has been found to lessen anxiety in mice by diminishing the number of memories that are based on a generalized sense of fear. This effect was shown when the animals were given MGT.

MGT is often taken in a dose ranging from 1,500 mg to 2,000 mg per day, which is then split across three capsules. If you are taking the supplement in capsule form, you should take one capsule upon waking up and another two capsules just before retiring to bed.